Pentoprazole can be taken at any time. That said, if you develop intense stomach pain accompanied by diarrhea and/or fever while using pantoprazole, it could be a sign of Clostridium difficile infection. Stomach pain: In clinical trials of adults diagnosed with gastroesophageal reflux disease (GERD), stomach pain was reported in approximately 6.2% of pantoprazole users as a side effect. Gas (flatulence): Yet another side effect associated with pantoprazole is increased gassiness or flatulence. Most individuals who develop insomnia specifically from pantoprazole will probably want to discontinue pantoprazole and transition to another medication. Research is underway to discover the potential aspirin has as a cancer preventative. In the event that you experience vomiting at any point during treatment, report it to your doctor as soon as possible – vomiting could be the sign of a serious adverse reaction. Pentoprazole and rabeprazole are commomly called as PPI i. e. Proton pump inhibitors. If you notice frequent urges to pass gas, or gas buildup throughout your stomach – know that this might be attributable to pantoprazole. Weight loss as a side effect may be a downstream byproduct of other relatively common side effects such as: diarrhea, nausea, and vomiting. Assuming you’re using the standard recommended pantoprazole dose, risk of side effects should be relatively low – and if side effects occur, they’re unlikely to be severe. The specific dose of pantoprazole that you administer throughout treatment might determine the side effects that you experience, and the intensities of your side effects. Included below is a list of side effects associated with pantoprazole that you might experience throughout treatment. There are numerous variables that might influence the particular side effects and/or adverse reactions that you experience while using pantoprazole. New comments cannot be posted and votes cannot be cast, More posts from the EosinophilicE community, For people with EE. Taking venlafaxine can result in a false positive urine test for PCP. Pantoprazole is a proton pump inhibitor that decreases acid secretion in the stomach and may be given to relieve the symptoms of heartburn or to allow inflamed tissue in the gastrointestinal tract to heal. In most cases, treating GERD with a medication like pantoprazole should decrease the frequency of burping and/or belching. Learn more: Mayo Clinic facts about coronavirus disease 2019 (COVID-19) Our COVID-19 patient and visitor guidelines, plus trusted health information Latest on COVID-19 vaccination by site: Arizona patient vaccination updates Arizona, Florida patient vaccination … In the event that you’re using pantoprazole (or previously used it), discuss all side effects that you’ve experienced as a result of the medication – in the comments section below. GERD and anxiety can cause a number of different symptoms, though there are a few that both conditions seem to have in common. I've been on it for about a year or two. Anxiolytics are used to treat several types of anxiety disorders. To counteract the bloating, it is recommended to drink plenty of water and avoid consuming excessive calories. You can connect with a US based physician from your state to seek medical advice and if they feel it is safe and appropriate for you to get treatment then it may result in a prescription. Tcurrently these are best drugs for acid reflux, commonly combined with domperidome for anti emetic effect. Vomiting: Although nausea is a common side effect of pantoprazole, vomiting is less common. It is unknown as to whether the reaction of dizziness is directly caused by the medication – or an indirect downstream reaction stemming from another more common side effect like diarrhea or vomiting. Over lots of trial and error with medication, eating habits, and activites I've found a way to feel normal and not have to live with pain everyday. Histamine blockers, or H2 blockers, were the drug of choice for acid reflux (GERD) prior to the introduction of proton pump inhibitors (PPIs). If you develop insomnia along with other neuropsychiatric symptoms such as anxiety, agitation, and restlessness while using pantoprazole – report this reaction to a medical doctor as soon as possible. 44% of those users who reviewed Pantoprazole reported a positive effect, while 39% reported a negative effect. The mechanism of action of an anxiolytic drug depends upon the specific drug class to which it belongs. You can also subscribe without commenting. If, at any point throughout pantoprazole treatment you have a question or concern regarding a side effect, it is recommended to consult a medical doctor. Unfortunately though, I’ve had my fair share of side affects. Examples of some medications that may interact with pantoprazole include: atazanavir, nelfinavir, ampicillin, blood thinners, digoxin, diuretics (water pills), ketoconazole, iron, methotrexate, amphetamine, and mycophenolate mofetil. Psychiatric reactions to pantoprazole are considered rare but can occur. I switched to omeprazole, and problem solved! Press question mark to learn the rest of the keyboard shortcuts. Each dose contains 5 milligrams (mg) of chlordiazepoxide and 2.5 mg of clidinium. Before the allergic reactions happened I did also have some pretty bad intestinal upset. For example, if you’re taking a medication with pantoprazole that causes nausea – this side effect may end up more pronounced than it otherwise would’ve been due to the fact that both medications are contributing to the nausea. lifestyle, genetics, preexisting medical conditions). Moreover, vomiting is generally preceded by nausea and may be accompanied by stomach pain. If you’re taking pantoprazole and notice that you’re burping more than you were before taking it, discuss this with your doctor – it could be a sign that the medication is not fully managing your symptoms. In short, understand that side effects may be contingent upon how long you’ve taken pantoprazole. arthritis), your preexisting joint pain may worsen from pantoprazole. Anxiolytics (anti-anxiety drugs) is a drug class that is comprised of other types of drug classes, for example, benzodiazepines, antidepressants, and anticonvulsants. Additionally, there’s a chance that some side effects of pantoprazole will be exacerbated by concurrent substance use via synergistic actions. Although food doesn’t get stuck in my throat, it still feels like the muscle in the back of my throat is weak and has a hard time pulling the food down. Included below are some strategies that might prove useful for reducing the prevalence and/or severities of side effects that are caused by pantoprazole. I had a 90 day supply that I've been milking for the past couple months since my GI doc stopped accepting my insurance and I haven't been able to get around to getting a referral to a new GI. When I was diagnosed in 2010 I had no idea what it was and no resources. If you’re using a dose that’s even lower than the standard recommended dose, risk of side effects will be further reduced (largely because there’s less pantoprazole interacting with your physiology). Otherwise, my experience has been positive. Learn how your comment data is processed. You, as a reader of this website, are totally and completely responsible for your own health and healthcare. The specific format of pantoprazole that you’re using might influence the prevalence and/or severities of certain side effects. If an injection site reaction continues to worsen in appearance, seek emergency medical attention to rule out an infection. If you’re using pantoprazole, it is important to be informed of potential side effects and adverse reactions that could occur. anxiety, the usual dose is 40mg once a day which can be increased to 40mg 3 times a day. If you end up losing weight while taking pantoprazole, dizziness could be due to rapid weight loss or malnourishment. Burping: A fairly common symptom of GERD (gastroesophageal reflux disease) is frequent burping or belching, along with heartburn. to a significant extent. Doses are usually lower for the elderly or people with a kidney or liver problem. I have tried a couple different PPIs. Fatigue and drowsiness might impair motor function such that you may exhibit delayed reaction, compromised mental acuity, and/or suboptimal coordination – all of which could increase your risk of accidents. What up my EOE peeps? Thank you for the advice, I will mention that to my doc. They are however some of the highest quality products one could obtain … Variables that probably influence the specific side effects of pantoprazole that you experience (and the severities of those side effects) include: pantoprazole dose; length of pantoprazole use; pantoprazole format; user-specific factors (e.g. Pantoprazole is manufactured in the following formats: oral (delayed-release tablets and delayed-release oral suspension) and injectable (intravenous solution). Common injection site reactions include: redness, pain, swelling, itchiness, and/or discoloration around the specific site of injection. My esophageal and stomach issues due to the EoE were completely gone, but I get decent relief without the side effects on omeprazole. omeprazole, rabeprazole, pantoprazole or lansoprazole on testosterone plasma levels or other hormones like prolactin was found [7-11]. If you’re aware of additional pantoprazole side effects and/or adverse reactions that could occur, mention these reactions in the comments – preferably with a medical source to substantiate your information. If you don’t respond well to pantoprazole or cannot tolerate its side effects – there are effective alternative medications that a medical doctor can recommend. Pantoprazole oral tablet is a prescription drug that’s available as the brand-name drug Protonix.It’s also available as a generic drug. If you’re a new pantoprazole user and are experiencing fatigue or drowsiness, understand that this could be a transient reaction that dissipates with continued longer-term pantoprazole administration. In other words, certain side effects might occur and/or be pronounced in the first few days or weeks of treatment due to the fact that the body hasn’t adjusted itself to the presence of pantoprazole. © MentalHealthDaily.com 2013-2019 | Privacy Policy | Legal Notice | Affiliate Disclosure, Pantoprazole (Protonix) vs. Omeprazole (Prilosec), Lamictal Side Effects & Adverse Reactions, Kombucha Side Effects & Adverse Reactions (List of Possibilities), Belviq (Lorcaserin) Side Effects & Adverse Reactions (List), Krill Oil Side Effects & Adverse Reactions. Notify me of followup comments via e-mail. Next post: How Long Does It Take For Lexapro To Work? Included below is a list of relatively uncommon or rare adverse reactions to pantoprazole treatment. Oppositely, the lower the dose of pantoprazole that’s administered, the lesser its effect will be upon H+/K+ ATPase. The daily dosage can vary by the condition being treated.1 For best results, Librax should be taken 30 minutes to one hour before eating a meal and right before bedtime. Librax is available in a capsule formulation. My symptoms were mostly headache (seriously would not relent) and constipation with the pantoprazole. Because the medication decreases acidification of the stomach, the absorption and digestion of food changes. 5 evaluations from gastroesophageal reflux disease patients report moderate overall side effects for Pantoprazole (16%) 3 evaluations from gastroesophageal reflux disease patients report mild overall side effects for Pantoprazole (9%) 22 evaluations from gastroesophageal reflux disease patients report no overall side effects for Pantoprazole (70%) Correcting vitamin and mineral deficiencies might help alleviate headaches as a side effect. 12) Antidepressants. acute interstitial nephritis) or less common side effects such as bloating, edema, and constipation. rumbling stomach, diarrhea, etc.). Nausea: Nausea, or feeling as though you’re on the verge of vomiting, is a side effect that occurs in around 7% of pantoprazole users. Stress and anxiety is found among people who take Pantoprazole, especially for people who are female, 60+ old, have been taking the drug for < 1 month. Note: The author of this site is not engaged in rendering professional advice or services to the individual reader. Reports from pantoprazole trials indicate that around 3.9% of users experienced flatulence as a side effect. Furthermore, both diarrhea and vomiting can dehydrate the body, leading to loss of water weight. For certain individuals, side effects that emerge in the early days of treatment will eventually fade with continued pantoprazole administration as the body becomes better adjusted to the medication’s presence. Assuming you’ve dealt with some disconcerting side effects while using pantoprazole, are there any strategies that you’ve employed to decrease these side effects? Pantoprazole tablets are delayed-release and should not be split, crushed, or chewed; pantoprazole oral granules are available. Moreover, because pantoprazole is metabolized by the CYP2C19 enzyme, any concurrently-used medication that interacts with CYP2C19 might increase risk of side effects. There may be adjunct interventions that could help increase your alertness and energy. Someone who recently initiated pantoprazole treatment may experience side effects that are attributable to lack of physiologic adjustment to its effect. It is understood that administration instructions may slightly differ between various formats of pantoprazole. Has anyone else experienced this? Medications that alter the pH of the stomach may be most likely to provoke interaction effects among pantoprazole users. Note: The above lists of pantoprazole side effects and adverse reactions might be incomplete. If you’re experiencing diarrhea or vomiting, your body may not be absorbing as many calories as it was prior to taking pantoprazole – ultimately causing reduced body weight. Previous post: How Long Does It Take For Zoloft To Work or “Kick In”? In any regard, most persons using pantoprazole are probably willing to put up with bloating as long as the medication is alleviating their gastric symptoms. Disproportionality in the WHO The phase IV clinical study is created by eHealthMe based on reports of 151,969 people who have side effects when taking Pantoprazole from the FDA, and is updated regularly. In most cases, joint pain as a side effect of pantoprazole will be of mild intensity and/or intermittent (such that it won’t occur nonstop). ENT appt was last week, and endoscopy is scheduled for next week. This is my first official reddit post, but I’ve been a reader for years. On the other hand, weight gain from pantoprazole might occur as a result of a severe adverse reaction (e.g. According to clinical research, the most common side effects of pantoprazole include: headache, diarrhea, nausea, abdominal pain, flatulence, vomiting dizziness, and joint pain. According to clinical research, there are no significant differences between pantoprazole formats in terms of physiologic effect and efficacy; each of the formats facilitate similar effects. Celexa (Citalopram) vs. Lexapro (Escitalopram): Which Is Better? Identification Name Pantoprazole Accession Number DB00213 Description. This is because high doses of pantoprazole modulate physiology (e.g. If you take other medications or supplements while using pantoprazole, have you considered that the side effects you’re experiencing may be more attributable to those other agents than pantoprazole? Always inform your doctor of substances that you plan on using along with pantoprazole to ensure that those substances are safe. Amitriptyline (Elavil) Withdrawal Symptoms + How Long Do They Last? In some cases, insomnia while using pantoprazole could be due to: changes in gut bacteria or the occurrence of late-night gastrointestinal side effects (e.g. ---------------------------------------------------------- Nausea generally occurs as a side effect of pantoprazole due to the fact that the medication suppresses acid production within the gastrointestinal tract. About Medzino. Individuals with preexisting neuropsychiatric disorders such as: anxiety and/or depression may be at increased risk of developing insomnia as a side effect compared to those without neuropsychiatric disorders. If you experience severe bloating such that various parts of your body (e.g. Instead of treating the cause of the anxiety & depression, the doctors loaded me up on cocktails of antidepressants and anti-anxiety … Because long-term pantoprazole therapy can sometimes interfere with the absorption of vitamins and minerals, it’s possible that the side effect of headache is explained by a vitamin deficiency – particularly in vitamin B12, vitamin C, calcium, iron, and magnesium. It is important to underscore the fact that, although certain side effects of pantoprazole may be more common than others, the specific side effects experienced – as well as the severities of those side effects – will be subject to significant interindividual variation among users. Because pantoprazole increases risk of Clostridium difficile infection, it is recommended to have your doctor rule out infection if you experience abdominal pain or intense stomach aches. Lexapro (Escitalopram) vs Zoloft (Sertraline): Extensive Comparison. Although many individuals with gastrointestinal dysfunction derive therapeutic benefit from the ability of pantoprazole to inhibit acid secretion, the medication can cause side effects, some of which may be unpleasant. It was giving me terrible heartburn to the point where I thought I was having a heart attack. If you’re experiencing stomach aches or abdominal pain while using pantoprazole, understand that this is the fourth most common side effect of the medication. That said, most bloating from the medication won’t be associated with a severe reaction – and will probably be caused by altered gastrointestinal activity, leading to gas and fluid accumulation. On the other hand, if you’re administering a high dose of pantoprazole that exceeds that standard recommended dose, your risk of developing severe side effects and adverse reactions dramatically increases. Aspirin, the simple, white headache reliever you buy over the counter, has more health benefits than you may think. Sometimes, pantoprazole is taken for a rare illness caused by a tumour in the pancreas or gut called Zollinger-Ellison syndrome. Lexapro (Escitalopram) vs. Prozac (Fluoxetine), Pregabalin (Lyrica) vs. Gabapentin (Neurontin). Similarly, another medication used with pantoprazole may augment its suppression of stomach acid – leading to a stronger effect and more prevalent side effects. He said this should provide immediate relief while we wait for the endoscopy. 2 months). Because pantoprazole increases risk of the bacterial infection Clostridium difficile (C. diff), and this particular infection induces diarrhea, it is recommended to get tested for Clostridium difficile associated diarrhea (CDAD) throughout treatment. In clinical trials of pantoprazole (20 mg or 40 mg), vomiting occurred in 4.3% of recipients. Bloating: Pantoprazole treatment may cause bloating as a side effect such that some users may report feeling swollen with fluid and/or gas. This site uses Akismet to reduce spam. Venlafaxine (Effexor XR) is a commonly prescribed serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant used for anxiety, depression, and menopausal hot flashes. If the nausea becomes severe enough to induce vomiting and/or interferes with your ability to function – report this to a medical doctor. Do most people with EoE have to take a PPI everyday for life? It's used for heartburn, acid reflux and gastro-oesophageal reflux disease (GORD) – GORD is when you keep getting acid reflux. In general, the higher the dose of pantoprazole that’s administered, the more substantial its effect will be upon H+/K+ (hydrogen/potassium) ATPase. Pharmaceutical Grade Pharmaceutical Grade products are those that are specifically designed for the medical purposes. Etc..). More specifically, pantoprazole covalently binds to the H+/K+ ATP pump whereby it suppresses secretion of gastric and basal acid for 24 hours (or more) following administration – hence its classification as a “proton pump inhibitor.”. The medication was originally synthesized in 1985 and received FDA approval in 2000 throughout the United States under the brand name “Protonix.”, Research indicates that, when pantoprazole is ingested, it interacts with parietal cells located inside of gastric glands to inhibit activation of H+/K+ (hydrogen/potassium) ATPase, an enzyme implicated in acidifying the stomach. The ideas, procedures, and suggestions contained within this work are not intended as a substitute for consulting with a medical doctor. Another medication used with pantoprazole could interfere with its therapeutic effect – leading to decreased efficacy. 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